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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of autoimmune uveitis
ncRNA name TLR3 siRNA
ncRNA Category siRNA
Disease name autoimmune uveitis
Species Mus musculus
Tissues/Cell_line mouse RPE cells
Methods qPCR, siRNA transfection, luciferase reporter assay, ELISA
Expression pattern associated
Functional description Chitosan-mediated TLR3-siRNA transfection had a significant therapeutic effect on either delaying the outbreak or remitting the severity of uveitis.
PubMed ID 24055691
Year 2013
Title Subretinal transfection of chitosan-loaded TLR3-siRNA for the treatment of experimental autoimmune uveitis.
Drug-related ncRNA NO

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